Alternative Magnesium Sulfate Dosing Regimens for Women With Preeclampsia: A Population Pharmacokinetic Exposure‐Response Modeling and Simulation Study

Magnesium sulfate is the anticonvulsant of choice for eclampsia prophylaxis and treatment; however, the recommended dosing regimens are costly and cumbersome and can be administered only by skilled health professionals. The objectives of this study were to develop a robust exposure‐response model fo...

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Detalhes bibliográficos
Publicado no:J Clin Pharmacol
Main Authors: Du, Lihong, Wenning, Larissa A., Carvalho, Brendan, Duley, Lelia, Brookfield, Kathleen F., Witjes, Han, de Greef, Rik, Lumbiganon, Pisake, Titapant, Vitaya, Kongwattanakul, Kiattisak, Long, Qian, Sangkomkamhang, Ussanee S., Gülmezoglu, Ahmet M., Oladapo, Olufemi T.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Women's Health
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790709/
https://ncbi.nlm.nih.gov/pubmed/31157410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.1448
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