Pharmacokinetics and Pharmacodynamics of Once-Daily versus Twice-Daily Raltegravir in Treatment-Naïve HIV-Infected Patients

QDMRK was a phase III clinical trial of raltegravir given once daily (QD) (800-mg dose) versus twice daily (BID) (400 mg per dose), each in combination with once-daily coformulated tenofovir-emtricitabine, in treatment-naive HIV-infected patients. Pharmacokinetic (PK) and pharmacokinetic/pharmacodyn...

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Detalhes bibliográficos
Main Authors: Rizk, Matthew L., Hang, Yaming, Luo, Wen-Lin, Su, Jing, Zhao, Jing, Campbell, Havilland, Nguyen, Bach-Yen T., Sklar, Peter, Eron, Joseph J., Wenning, Larissa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370742/
https://ncbi.nlm.nih.gov/pubmed/22430964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06417-11
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