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Intracellular Pharmacokinetics of Once versus Twice Daily Zidovudine and Lamivudine in Adolescents
Zidovudine (ZDV) and lamivudine (3TC) metabolism to triphosphates (TP) is necessary for antiviral activity. The aims of this study were to compare ZDV-TP and 3TC-TP concentrations in adolescents receiving twice daily (BID) and once daily (QD) regimens and to determine the metabolite concentrations o...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology
2007
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2043291/ https://ncbi.nlm.nih.gov/pubmed/17664328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01626-06 |
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