Intracellular Pharmacokinetics of Once versus Twice Daily Zidovudine and Lamivudine in Adolescents

Zidovudine (ZDV) and lamivudine (3TC) metabolism to triphosphates (TP) is necessary for antiviral activity. The aims of this study were to compare ZDV-TP and 3TC-TP concentrations in adolescents receiving twice daily (BID) and once daily (QD) regimens and to determine the metabolite concentrations o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Flynn, Patricia M., Rodman, John, Lindsey, Jane C., Robbins, Brian, Capparelli, Edmund, Knapp, Katherine M., Rodriguez, Jose F., McNamara, James, Serchuck, Leslie, Heckman, Barbara, Martinez, Jaime
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043291/
https://ncbi.nlm.nih.gov/pubmed/17664328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01626-06
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge