Is the Recommended Once-Daily Dose of Lamivudine Optimal in West African HIV-Infected Children?

We aimed in this study to describe lamivudine concentration-time courses in treatment-naïve children after once-daily administration, to study the effects of body weight and age on lamivudine pharmacokinetics, and to simulate an optimized administration scheme. For this purpose, lamivudine concentra...

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Autors principals: Bouazza, Naïm, Hirt, Déborah, Bardin, Christophe, Diagbouga, Serge, Nacro, Boubacar, Hien, Hervé, Zoure, Emmanuelle, Rouet, François, Ouiminga, Adama, Blanche, Stephane, Van De Perre, Philippe, Tréluyer, Jean-Marc, Msellati, Philippe, Urien, Saik
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916343/
https://ncbi.nlm.nih.gov/pubmed/20516271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00306-10
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