Is the Recommended Dose of Efavirenz Optimal in Young West African Human Immunodeficiency Virus-Infected Children?

We aimed in this study to describe efavirenz concentration-time courses in treatment-naïve children after once-daily administration to study the effects of age and body weight on efavirenz pharmacokinetics and to test relationships between doses, plasma concentrations, and efficacy. For this purpose...

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Main Authors: Hirt, Déborah, Urien, Saik, Olivier, Mathieu, Peyrière, Hélène, Nacro, Boubacar, Diagbouga, Serge, Zoure, Emmanuelle, Rouet, François, Hien, Hervé, Msellati, Philippe, Van De Perre, Philippe, Tréluyer, Jean-Marc
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
主題:
Pharmacology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2764212/
https://ncbi.nlm.nih.gov/pubmed/19635964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01594-08
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