Equivalent Steady-State Pharmacokinetics of Lamivudine in Plasma and Lamivudine Triphosphate within Cells following Administration of Lamivudine at 300 Milligrams Once Daily and 150 Milligrams Twice Daily

Once-daily administration of 300 mg of lamivudine in combination with other antiretroviral agents has been proposed as a possible way to optimize anti-human immunodeficiency virus (HIV) treatment and to facilitate adherence. A single-center, randomized, two-way, crossover study was conducted in 60 h...

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Detalhes bibliográficos
Main Authors: Yuen, Geoffrey J., Lou, Yu, Bumgarner, Nancy F., Bishop, Jim P., Smith, Glenn A., Otto, Victoria R., Hoelscher, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC310153/
https://ncbi.nlm.nih.gov/pubmed/14693537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.1.176-182.2004
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