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Equivalent Steady-State Pharmacokinetics of Lamivudine in Plasma and Lamivudine Triphosphate within Cells following Administration of Lamivudine at 300 Milligrams Once Daily and 150 Milligrams Twice Daily

Once-daily administration of 300 mg of lamivudine in combination with other antiretroviral agents has been proposed as a possible way to optimize anti-human immunodeficiency virus (HIV) treatment and to facilitate adherence. A single-center, randomized, two-way, crossover study was conducted in 60 h...

Celý popis

Uloženo v:
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Yuen, Geoffrey J., Lou, Yu, Bumgarner, Nancy F., Bishop, Jim P., Smith, Glenn A., Otto, Victoria R., Hoelscher, David D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2004
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310153/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14693537/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.1.176-182.2004
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