Signal transduction STIM1 senses both Ca(2+) and heat

Por Mancarella, Salvatore, Wang, Youjun, Gill, Donald L
Publicado em 2011

Calcium Signals: STIM Dynamics Mediate Spatially Unique Oscillations

Por Mancarella, Salvatore, Wang, Youjun, Gill, Donald L.
Publicado em 2009

Calcium Signaling by STIM and Orai: Intimate Coupling Details Revealed

Por Wang, Youjun, Deng, Xiaoxiang, Gill, Donald L.
Publicado em 2010

Orai Channel Pore Properties and Gating by STIM: Implications from the Orai Crystal Structure

Por Rothberg, Brad S., Wang, Youjun, Gill, Donald L.
Publicado no Sci Signal (2013)

STIM and Orai: Dynamic Intermembrane Coupling to Control Cellular Calcium Signals

Por Deng, Xiaoxiang, Wang, Youjun, Zhou, Yandong, Soboloff, Jonathan, Gill, Donald L.
Publicado em 2009

STIM, ORAI AND TRPC CHANNELS IN THE CONTROL OF CALCIUM ENTRY SIGNALS IN SMOOTH MUSCLE

Por Wang, Youjun, Deng, Xiaoxiang, Hewavitharana, Thamara, Soboloff, Jonathan, Gill, Donald L
Publicado em 2008

The Short N-terminal Domains of STIM1 and STIM2 Control the Activation Kinetics of Orai1 Channels

Por Zhou, Yandong, Mancarella, Salvatore, Wang, Youjun, Yue, Chanyu, Ritchie, Michael, Gill, Donald L., Soboloff, Jonathan
Publicado em 2009

The short N-terminal domains of STIM1 and STIM2 control the activation kinetics of Orai1 channels.

Por Zhou, Yandong, Mancarella, Salvatore, Wang, Youjun, Yue, Chanyu, Ritchie, Michael, Gill, Donald L., Soboloff, Jonathan
Publicado em 2009

Location and Function of STIM1 in the Activation of Ca(2+) Entry Signals

Por Hewavitharana, Thamara, Deng, Xiaoxiang, Wang, Youjun, Ritchie, Michael F., Girish, Gannareddy V., Soboloff, Jonathan, Gill, Donald L.
Publicado em 2008

The Calcium Store Sensor, STIM1, Reciprocally Controls Orai and Ca(V)1.2 Channels

Por Wang, Youjun, Deng, Xiaoxiang, Mancarella, Salvatore, Hendron, Eunan, Eguchi, Satoru, Soboloff, Jonathan, Tang, Xiang D., Gill, Donald L.
Publicado em 2010

Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site

Por Wang, Xizhuo, Wang, Youjun, Zhou, Yandong, Hendron, Eunan, Mancarella, Salvatore, Andrake, Mark D., Rothberg, Brad S., Soboloff, Jonathan, Gill, Donald L.
Publicado em 2014

The Orai1 Store-operated Calcium Channel Functions as a Hexamer

Por Cai, Xiangyu, Zhou, Yandong, Nwokonko, Robert M., Loktionova, Natalia A., Wang, Xianming, Xin, Ping, Trebak, Mohamed, Wang, Youjun, Gill, Donald L.
Publicado no J Biol Chem (2016)

Potent functional uncoupling between STIM1 and Orai1 by dimeric 2-aminodiphenyl borinate analogs

Por Hendron, Eunan, Wang, Xizhuo, Zhou, Yandong, Cai, Xiangyu, Goto, Jun-Ichi, Mikoshiba, Katsuhiko, Baba, Yoshihiro, Kurosaki, Tomohiro, Wang, Youjun, Gill, Donald L.
Publicado no Cell Calcium (2014)

Hypoxia-induced Acidosis Uncouples the STIM-Orai Calcium Signaling Complex

Por Mancarella, Salvatore, Wang, Youjun, Deng, Xiaoxiang, Landesberg, Gavin, Scalia, Rosario, Panettieri, Reynold A., Mallilankaraman, Karthik, Tang, Xiang D., Madesh, Muniswamy, Gill, Donald L.
Publicado em 2011

STIM1 dimers undergo unimolecular coupling to activate Orai1 channels

Por Zhou, Yandong, Wang, Xizhuo, Wang, Xianming, Loktionova, Natalia A., Cai, Xiangyu, Nwokonko, Robert M., Vrana, Erin, Wang, Youjun, Rothberg, Brad S., Gill, Donald L.
Publicado no Nat Commun (2015)

The STIM1-binding site nexus remotely controls Orai1 channel gating

Por Zhou, Yandong, Cai, Xiangyu, Loktionova, Natalia A., Wang, Xianming, Nwokonko, Robert M., Wang, Xizhuo, Wang, Youjun, Rothberg, Brad S., Trebak, Mohamed, Gill, Donald L.
Publicado no Nat Commun (2016)

Molecular mechanisms of inhibition on STIM1-Orai1 mediated Ca(2+) entry induced by 2-aminoethoxydiphenyl borate

Por Wei, Ming, Zhou, Yandong, Sun, Aomin, Ma, Guolin, He, Lian, Zhou, Lijuan, Zhang, Shuce, Liu, Jin, Zhang, Shenyuan L., Gill, Donald L., Wang, Youjun
Publicado no Pflugers Arch (2016)

STIM protein coupling in the activation of Orai channels

Por Wang, Youjun, Deng, Xiaoxiang, Zhou, Yandong, Hendron, Eunan, Mancarella, Salvatore, Ritchie, Michael F., Tang, Xiang D., Baba, Yoshihiro, Kurosaki, Tomohiro, Mori, Yasuo, Soboloff, Jonathan, Gill, Donald L.
Publicado em 2009

Targeted STIM deletion impairs calcium homeostasis, NFAT activation, and growth of smooth muscle

Por Mancarella, Salvatore, Potireddy, Santhi, Wang, Youjun, Gao, Hui, Gandhirajan, Rajesh Kumar, Autieri, Michael, Scalia, Rosario, Cheng, Zhongjian, Wang, Hong, Madesh, Muniswamy, Houser, Steven R., Gill, Donald L.
Publicado em 2013

Near-infrared photoactivatable control of Ca(2+) signaling and optogenetic immunomodulation

Por He, Lian, Zhang, Yuanwei, Ma, Guolin, Tan, Peng, Li, Zhanjun, Zang, Shengbing, Wu, Xiang, Jing, Ji, Fang, Shaohai, Zhou, Lijuan, Wang, Youjun, Huang, Yun, Hogan, Patrick G, Han, Gang, Zhou, Yubin
Publicado no eLife (2015)