Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)

Por Yang, Xue, Jin, Hao, Cai, Xiangyu, Li, Siwei, Shen, Yuequan
Publicado em 2012

Structure of Neisseria meningitidis lipoprotein GNA1162

Por Cai, Xiangyu, Lu, Jing, Wu, Zhenhua, Yang, Chunting, Xu, Honglin, Lin, Zhijie, Shen, Yuequan
Publicado em 2013

The STIM-Orai coupling interface and gating of the Orai1 channel

Por Zhou, Yandong, Cai, Xiangyu, Nwokonko, Robert M., Loktionova, Natalia A., Wang, Youjun, Gill, Donald L.
Publicado no Cell Calcium (2017)

CpG-ODN Attenuates Pathological Cardiac Hypertrophy and Heart Failure by Activation of PI3Kα-Akt Signaling

Por Yang, Liang, Cai, Xiangyu, Liu, Jie, Jia, Zhe, Jiao, Jinjin, Zhang, Jincai, Li, Changlin, Li, Jing, Tang, Xiang D.
Publicado em 2013

The Orai1 Store-operated Calcium Channel Functions as a Hexamer

Por Cai, Xiangyu, Zhou, Yandong, Nwokonko, Robert M., Loktionova, Natalia A., Wang, Xianming, Xin, Ping, Trebak, Mohamed, Wang, Youjun, Gill, Donald L.
Publicado no J Biol Chem (2016)

Potent functional uncoupling between STIM1 and Orai1 by dimeric 2-aminodiphenyl borinate analogs

Por Hendron, Eunan, Wang, Xizhuo, Zhou, Yandong, Cai, Xiangyu, Goto, Jun-Ichi, Mikoshiba, Katsuhiko, Baba, Yoshihiro, Kurosaki, Tomohiro, Wang, Youjun, Gill, Donald L.
Publicado no Cell Calcium (2014)

The δA isoform of calmodulin kinase II mediates pathological cardiac hypertrophy by interfering with the HDAC4-MEF2 signaling pathway

Por Li, Changlin, Cai, Xiangyu, Sun, Haili, Bai, Ting, Zheng, Xilong, Zhou, Xing Wang, Chen, Xiongwen, Gill, Donald L., Li, Jing, Tang, Xiang D.
Publicado em 2011

Protein Kinase D3 Is a Pivotal Activator of Pathological Cardiac Hypertrophy by Selectively Increasing the Expression of Hypertrophic Transcription Factors

Por Li, Changlin, Li, Jing, Cai, Xiangyu, Sun, Haili, Jiao, Jinjin, Bai, Ting, Zhou, Xing Wang, Chen, Xiongwen, Gill, Donald L., Tang, Xiang D.
Publicado em 2011

STIM1 dimers undergo unimolecular coupling to activate Orai1 channels

Por Zhou, Yandong, Wang, Xizhuo, Wang, Xianming, Loktionova, Natalia A., Cai, Xiangyu, Nwokonko, Robert M., Vrana, Erin, Wang, Youjun, Rothberg, Brad S., Gill, Donald L.
Publicado no Nat Commun (2015)

The STIM1-binding site nexus remotely controls Orai1 channel gating

Por Zhou, Yandong, Cai, Xiangyu, Loktionova, Natalia A., Wang, Xianming, Nwokonko, Robert M., Wang, Xizhuo, Wang, Youjun, Rothberg, Brad S., Trebak, Mohamed, Gill, Donald L.
Publicado no Nat Commun (2016)