Protein Kinase D3 Is a Pivotal Activator of Pathological Cardiac Hypertrophy by Selectively Increasing the Expression of Hypertrophic Transcription Factors

Fetal cardiac gene reactivation is a hallmark of pathological cardiac hypertrophy (PCH) driven by cardiac transcription factors (TFs) such as nuclear factor of activated T-cells (NFATs). Nuclear import of dephosphorylated NFATs catalyzed by calcineurin (CaN) is a well-established hypertrophic mechan...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Li, Changlin, Li, Jing, Cai, Xiangyu, Sun, Haili, Jiao, Jinjin, Bai, Ting, Zhou, Xing Wang, Chen, Xiongwen, Gill, Donald L., Tang, Xiang D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Molecular Bases of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220477/
https://ncbi.nlm.nih.gov/pubmed/21971046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.263046
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