The δA isoform of calmodulin kinase II mediates pathological cardiac hypertrophy by interfering with the HDAC4-MEF2 signaling pathway

Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is a new promising target for prevention and treatment of cardiac hypertrophy and heart failure. There are 3 δ isoforms of CaMKII in the heart and previous studies focused primarily on δB and δC types. Here we report the δA isoform of CaMKII is...

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Main Authors: Li, Changlin, Cai, Xiangyu, Sun, Haili, Bai, Ting, Zheng, Xilong, Zhou, Xing Wang, Chen, Xiongwen, Gill, Donald L., Li, Jing, Tang, Xiang D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3113443/
https://ncbi.nlm.nih.gov/pubmed/21554860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.04.128
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