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The δ isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload
Acute and chronic injuries to the heart result in perturbation of intracellular calcium signaling, which leads to pathological cardiac hypertrophy and remodeling. Calcium/calmodulin-dependent protein kinase II (CaMKII) has been implicated in the transduction of calcium signals in the heart, but the...
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| Autori principali: | , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650158/ https://ncbi.nlm.nih.gov/pubmed/19179290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813013106 |
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