Cardiac CaM Kinase II Genes δ and γ Contribute to Adverse Remodeling but Redundantly Inhibit Calcineurin-Induced Myocardial Hypertrophy

BACKGROUND: Ca(2+)-dependent signaling through CaM Kinase II (CaMKII) and calcineurin was suggested to contribute to adverse cardiac remodeling. However, the relative importance of CaMKII versus calcineurin for adverse cardiac remodeling remained unclear. METHODS AND RESULTS: We generated double-kno...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Kreusser, Michael M., Lehmann, Lorenz H., Keranov, Stanislav, Hoting, Marc-Oscar, Oehl, Ulrike, Kohlhaas, Michael, Reil, Jan-Christian, Neumann, Kay, Schneider, Michael D., Hill, Joseph A., Dobrev, Dobromir, Maack, Christoph, Maier, Lars S., Gröne, Hermann-Josef, Katus, Hugo A., Olson, Eric N., Backs, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316667/
https://ncbi.nlm.nih.gov/pubmed/25124496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.006185
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados