Overexpression of miR-223 Tips the Balance of Pro- and Anti-hypertrophic Signaling Cascades toward Physiologic Cardiac Hypertrophy

MicroRNAs (miRNAs) have been extensively examined in pathological cardiac hypertrophy. However, few studies focused on profiling the miRNA alterations in physiological hypertrophic hearts. In this study we generated a transgenic mouse model with cardiac-specific overexpression of miR-223. Our result...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Yang, Liwang, Li, Yutian, Wang, Xiaohong, Mu, Xingjiang, Qin, Dongze, Huang, Wei, Alshahrani, Saeed, Nieman, Michelle, Peng, Jiangtong, Essandoh, Kobina, Peng, Tianqing, Wang, Yigang, Lorenz, John, Soleimani, Manoocher, Zhao, Zhi-Qing, Fan, Guo-Chang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Molecular Bases of Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957053/
https://ncbi.nlm.nih.gov/pubmed/27226563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715805
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