Overexpression of miR-223 Tips the Balance of Pro- and Anti-hypertrophic Signaling Cascades toward Physiologic Cardiac Hypertrophy

MicroRNAs (miRNAs) have been extensively examined in pathological cardiac hypertrophy. However, few studies focused on profiling the miRNA alterations in physiological hypertrophic hearts. In this study we generated a transgenic mouse model with cardiac-specific overexpression of miR-223. Our result...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yang, Liwang, Li, Yutian, Wang, Xiaohong, Mu, Xingjiang, Qin, Dongze, Huang, Wei, Alshahrani, Saeed, Nieman, Michelle, Peng, Jiangtong, Essandoh, Kobina, Peng, Tianqing, Wang, Yigang, Lorenz, John, Soleimani, Manoocher, Zhao, Zhi-Qing, Fan, Guo-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957053/
https://ncbi.nlm.nih.gov/pubmed/27226563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715805
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