Hsp20-Mediated Activation of Exosome Biogenesis in Cardiomyocytes Improves Cardiac Function and Angiogenesis in Diabetic Mice

Decreased heat shock protein (Hsp) expression in type 1 and type 2 diabetes has been implicated as a primary factor contributing to diabetes-induced organ damage. We recently showed that diabetic cardiomyocytes could release detrimental exosomes, which contain lower levels of Hsp20 than normal ones....

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Wang, Xiaohong, Gu, Haitao, Huang, Wei, Peng, Jiangtong, Li, Yutian, Yang, Liwang, Qin, Dongze, Essandoh, Kobina, Wang, Yigang, Peng, Tianqing, Fan, Guo-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5033265/
https://ncbi.nlm.nih.gov/pubmed/27284111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1563
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