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Circulating Exosomes Isolated from Septic Mice Induce Cardiovascular Hyperpermeability through Promoting Podosome Cluster Formation

Septic shock increases vascular permeability, leading to multiple organ failure including cardiac dysfunction, a major contributor to septic death. Podosome, an actin-based dynamic membrane structure, plays critical roles in extracellular matrix degradation and angiogenesis. However, whether podosom...

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Bibliographic Details
Published in:Shock
Main Authors: Mu, Xingjiang, Wang, Xiaohong, Huang, Wei, Wang, Rui-Tao, Essandoh, Kobina, Li, Yutian, Pugh, Amanda M, Peng, Jiangtong, Deng, Shan, Wang, Yigang, Caldwell, Charles C., Peng, Tianqing, Yu, Kai-Jiang, Fan, Guo-Chang
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742088/
https://ncbi.nlm.nih.gov/pubmed/28650928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000928
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