MicroRNA-223-5p and -3p Cooperatively Suppress Necroptosis in Ischemic/Reperfused Hearts

Recent studies have shown that myocardial ischemia/reperfusion (I/R)-induced necrosis can be controlled by multiple genes. In this study, we observed that both strands (5p and 3p) of miR-223 were remarkably dysregulated in mouse hearts upon I/R. Precursor miR-223 (pre-miR-223) transgenic mouse heart...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Qin, Dongze, Wang, Xiaohong, Li, Yutian, Yang, Liwang, Wang, Ruitao, Peng, Jiangtong, Essandoh, Kobina, Mu, Xingjiang, Peng, Tianqing, Han, Qinghua, Yu, Kai-Jiang, Fan, Guo-Chang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2016
Pynciau:
Molecular Bases of Disease
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025706/
https://ncbi.nlm.nih.gov/pubmed/27502281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.732735
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