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Exosomal miR-223 Contributes to Mesenchymal Stem Cell-Elicited Cardioprotection in Polymicrobial Sepsis

Mesenchymal stem cells (MSCs) have been shown to elicit cardio-protective effects in sepsis. However, the underlying mechanism remains obscure. While recent studies have indicated that miR-223 is highly enriched in MSC-derived exosomes, whether exosomal miR-223 contributes to MSC-mediated cardio-pro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wang, Xiaohong, Gu, Haitao, Qin, Dongze, Yang, Liwang, Huang, Wei, Essandoh, Kobina, Wang, Yigang, Caldwell, Charles C., Peng, Tianqing, Zingarelli, Basilia, Fan, Guo-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4562230/
https://ncbi.nlm.nih.gov/pubmed/26348153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13721
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