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Loss of MiR-223 Duplex (5p and 3p) Aggravates Myocardial Depression and Mortality in Polymicrobial Sepsis

Sepsis is the leading cause of death in critically ill patients. While myocardial dysfunction has been recognized as a major manifestation in severe sepsis, the underlying molecular mechanisms associated with septic cardiomyopathy remain unclear. In this study, we performed a miRNA array analysis in...

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Detalhes bibliográficos
Main Authors: Wang, Xiaohong, Huang, Wei, Yang, Yang, Wang, Yigang, Peng, Tianqing, Chang, Jiang, Caldwell, Charles C., Zingarelli, Basilia, Fan, Guo-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959587/
https://ncbi.nlm.nih.gov/pubmed/24486439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.01.012
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