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INDUCTION OF ENDOTOXIN TOLERANCE ENHANCES BACTERIAL CLEARANCE AND SURVIVAL IN MURINE POLYMICROBIAL SEPSIS

The fundamental mechanisms that underlie endotoxin tolerance remain to be elucidated, and the clinical significance of endotoxin tolerance in the context of active systemic infection remains in question. We hypothesized that the endotoxin tolerance phenotype would result in decreased inflammation at...

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Main Authors: Wheeler, Derek S., Lahni, Patrick M., Denenberg, Alvin G., Poynter, Sue E., Wong, Hector R., Cook, James A., Zingarelli, Basilia
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754132/
https://ncbi.nlm.nih.gov/pubmed/18197145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/shk.0b013e318162c190
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