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INDUCTION OF ENDOTOXIN TOLERANCE ENHANCES BACTERIAL CLEARANCE AND SURVIVAL IN MURINE POLYMICROBIAL SEPSIS

The fundamental mechanisms that underlie endotoxin tolerance remain to be elucidated, and the clinical significance of endotoxin tolerance in the context of active systemic infection remains in question. We hypothesized that the endotoxin tolerance phenotype would result in decreased inflammation at...

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Библиографические подробности
Главные авторы: Wheeler, Derek S., Lahni, Patrick M., Denenberg, Alvin G., Poynter, Sue E., Wong, Hector R., Cook, James A., Zingarelli, Basilia
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754132/
https://ncbi.nlm.nih.gov/pubmed/18197145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/shk.0b013e318162c190
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