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INDUCTION OF ENDOTOXIN TOLERANCE ENHANCES BACTERIAL CLEARANCE AND SURVIVAL IN MURINE POLYMICROBIAL SEPSIS

The fundamental mechanisms that underlie endotoxin tolerance remain to be elucidated, and the clinical significance of endotoxin tolerance in the context of active systemic infection remains in question. We hypothesized that the endotoxin tolerance phenotype would result in decreased inflammation at...

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Detalhes bibliográficos
Main Authors: Wheeler, Derek S., Lahni, Patrick M., Denenberg, Alvin G., Poynter, Sue E., Wong, Hector R., Cook, James A., Zingarelli, Basilia
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754132/
https://ncbi.nlm.nih.gov/pubmed/18197145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/shk.0b013e318162c190
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