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Blockade of Exosome Generation with GW4869 Dampens the Sepsis-Induced Inflammation and Cardiac Dysfunction

Sepsis is an infection-induced severe inflammatory disorder that leads to multiple organ failure. Amongst organs affected, myocardial depression is believed to be a major contributor to septic death. While it has been identified that large amounts of circulating pro-inflammatory cytokines are culpri...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Essandoh, Kobina, Yang, Liwang, Wang, Xiaohong, Huang, Wei, Qin, Dongze, Hao, Jiukuan, Wang, Yigang, Zingarelli, Basilia, Peng, Tianqing, Fan, Guo-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581992/
https://ncbi.nlm.nih.gov/pubmed/26300484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2015.08.010
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