Blockade of lncRNA-ASLNCS5088–enriched exosome generation in M2 macrophages by GW4869 dampens the effect of M2 macrophages on orchestrating fibroblast activation

In hypertrophic scar (HS) formation, the type 2 immune response induces the alternatively activated macrophages (M2), which manipulate fibroblasts to differentiate into myofibroblasts with active biologic functions and proliferation. Myofibroblasts express α-smooth muscle actin (α-SMA) and synthesiz...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Chen, Jialin, Zhou, Renpeng, Liang, Yimin, Fu, Xiujun, Wang, Danru, Wang, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902732/
https://ncbi.nlm.nih.gov/pubmed/31373848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901610
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