Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869

Zika virus (ZIKV) is a neurotrophic flavivirus that is capable of infecting humans, leading to brain abnormalities during fetal development. The ZIKV infectivity in neural target cells remains poorly understood. Here, we found that ZIKV specifically infected glial fibrillary acidic protein- and S100...

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Detalhes bibliográficos
Publicado no:Cell Discov
Main Authors: Huang, Yunlong, Li, Yuju, Zhang, Hainan, Zhao, Runze, Jing, Ran, Xu, Yinghua, He, Miao, Peer, Justin, Kim, Yeong C., Luo, Jiangtao, Tong, Zenghan, Zheng, Jialin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5913238/
https://ncbi.nlm.nih.gov/pubmed/29707233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-018-0017-2
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