Knockout of the Na,K-ATPase α(2)-isoform in cardiac myocytes delays pressure overload-induced cardiac dysfunction

Por Rindler, Tara N., Lasko, Valerie M., Nieman, Michelle L., Okada, Motoi, Lorenz, John N., Lingrel, Jerry B
Publicado em 2013

Loss of NHE1 activity leads to reduced oxidative stress in heart and mitigates high-fat diet-induced myocardial stress

Por Prasad, Vikram, Lorenz, John N., Miller, Marian L., Vairamani, Kanimozhi, Nieman, Michelle L., Wang, Yigang, Shull, Gary E.
Publicado em 2013

Loss of the AE3 Cl(−)/HCO(−)(3) exchanger in mice affects rate-dependent inotropy and stress-related AKT signaling in heart

Por Prasad, Vikram, Lorenz, John N., Lasko, Valerie M., Nieman, Michelle L., Al Moamen, Nabeel J., Shull, Gary E.
Publicado em 2013

Renovascular hypertension using a modified two-kidney, one-clip approach in mice is not dependent on the α1 or α2 Na-K-ATPase ouabain-binding site

Por Lorenz, John N., Lasko, Valerie M., Nieman, Michelle L., Damhoff, Thomas, Prasad, Vikram, Beierwaltes, William H., Lingrel, Jerry B.
Publicado em 2011

Knockout of the Na,K-ATPase α(2)-isoform in the cardiovascular system does not alter basal blood pressure but prevents ACTH-induced hypertension

Por Rindler, Tara N., Dostanic, Iva, Lasko, Valerie M., Nieman, Michelle L., Neumann, Jonathan C., Lorenz, John N., Lingrel, Jerry B.
Publicado em 2011

SERCA2 Haploinsufficiency in a Mouse Model of Darier Disease Causes a Selective Predisposition to Heart Failure

Por Prasad, Vikram, Lorenz, John N., Lasko, Valerie M., Nieman, Michelle L., Huang, Wei, Wang, Yigang, Wieczorek, David W., Shull, Gary E.
Publicado no Biomed Res Int (2015)

Acute consumption of a high-fat diet prior to ischemia-reperfusion results in cardioprotection through NF-κB-dependent regulation of autophagic pathways

Por Haar, Lauren, Ren, Xiaoping, Liu, Yong, Koch, Sheryl E., Goines, Jillian, Tranter, Michael, Engevik, Melinda A., Nieman, Michelle, Rubinstein, Jack, Jones, W. Keith
Publicado no Am J Physiol Heart Circ Physiol (2014)

The non-diuretic hypotensive effects of thiazides are enhanced during volume depletion states

Por Alshahrani, Saeed, Rapoport, Robert M., Zahedi, Kamyar, Jiang, Min, Nieman, Michelle, Barone, Sharon, Meredith, Andrea L., Lorenz, John N., Rubinstein, Jack, Soleimani, Manoocher
Publicado no PLoS One (2017)

TGF-β1 mediates the hypertrophic cardiomyocyte growth induced by angiotensin II

Por Schultz, Jo El J., Witt, Sandra A., Glascock, Betty J., Nieman, Michelle L., Reiser, Peter J., Nix, Stacey L., Kimball, Thomas R., Doetschman, Thomas
Publicado em 2002

Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load

Por Lorenz, John N., Nieman, Michelle, Sabo, Jenine, Sanford, L. Philip, Hawkins, Jennifer A., Elitsur, Noeet, Gawenis, Lara R., Clarke, Lane L., Cohen, Mitchell B.
Publicado em 2003

Interaction between transcellular and paracellular water transport pathways through Aquaporin 5 and the tight junction complex

Por Kawedia, Jitesh D., Nieman, Michelle L., Boivin, Gregory P., Melvin, James E., Kikuchi, Ken-Ichiro, Hand, Arthur R., Lorenz, John N., Menon, Anil G.
Publicado em 2007

CLIC5 mutant mice are resistant to diet-induced obesity and exhibit gastric hemorrhaging and increased susceptibility to torpor

Por Bradford, Emily M., Miller, Marian L., Prasad, Vikram, Nieman, Michelle L., Gawenis, Lara R., Berryman, Mark, Lorenz, John N., Tso, Patrick, Shull, Gary E.
Publicado em 2010

Pharmacological and Activated Fibroblast Targeting of Gβγ-GRK2 After Myocardial Ischemia Attenuates Heart Failure Progression

Por Travers, Joshua G., Kamal, Fadia A., Valiente-Alandi, Iñigo, Nieman, Michelle L., Sargent, Michelle A., Lorenz, John N., Molkentin, Jeffery D., Blaxall, Burns C.
Publicado no J Am Coll Cardiol (2017)

Fibroblast growth factor-2 mediates pressure-induced hypertrophic response

Por Schultz, Jo El J., Witt, Sandra A., Nieman, Michelle L., Reiser, Peter J., Engle, Sandra J., Zhou, Ming, Pawlowski, Sharon A., Lorenz, John N., Kimball, Thomas R., Doetschman, Thomas
Publicado em 1999

Tranilast blunts the hypertrophic and fibrotic response to increased afterload independent of cardiomyocyte transient receptor potential vanilloid 2 channels

Por Koch, Sheryl E., Nieman, Michelle L., Robbins, Nathan, Slone, Samuel, Worley, Mariah, Green, Lisa C., Chen, Yamei, Barlow, Alexandria, Tranter, Michael, Wang, HongSheng, Lorenz, John N., Rubinstein, Jack
Publicado no J Cardiovasc Pharmacol (2018)

Impaired Cardiac Contractility in Mice Lacking Both the AE3 [Formula: see text] Exchanger and the NKCC1 Na(+)-K(+)-2Cl(–) Cotransporter: EFFECTS ON Ca(2+) HANDLING AND PROTEIN...

Por Prasad, Vikram, Bodi, Ilona, Meyer, Jamie W., Wang, Yigang, Ashraf, Muhammad, Engle, Sandra J., Doetschman, Thomas, Sisco, Karena, Nieman, Michelle L., Miller, Marian L., Lorenz, John N., Shull, Gary E.
Publicado em 2008

Overexpression of miR-223 Tips the Balance of Pro- and Anti-hypertrophic Signaling Cascades toward Physiologic Cardiac Hypertrophy

Por Yang, Liwang, Li, Yutian, Wang, Xiaohong, Mu, Xingjiang, Qin, Dongze, Huang, Wei, Alshahrani, Saeed, Nieman, Michelle, Peng, Jiangtong, Essandoh, Kobina, Peng, Tianqing, Wang, Yigang, Lorenz, John, Soleimani, Manoocher, Zhao, Zhi-Qing, Fan, Guo-Chang
Publicado no J Biol Chem (2016)