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The Orai1 Store-operated Calcium Channel Functions as a Hexamer

Orai channels mediate store-operated Ca(2+) signals crucial in regulating transcription in many cell types, and implicated in numerous immunological and inflammatory disorders. Despite their central importance, controversy surrounds the basic subunit structure of Orai channels, with several biochemi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cai, Xiangyu, Zhou, Yandong, Nwokonko, Robert M., Loktionova, Natalia A., Wang, Xianming, Xin, Ping, Trebak, Mohamed, Wang, Youjun, Gill, Donald L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207053/
https://ncbi.nlm.nih.gov/pubmed/27780862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.758813
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