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Pore properties of Orai1 calcium channel dimers and their activation by the STIM1 ER calcium sensor
Store-operated Ca(2+) entry signals are mediated by plasma membrane Orai channels activated through intermembrane coupling with Ca(2+)-sensing STIM proteins in the endoplasmic reticulum (ER). The nature of this elaborate Orai-gating mechanism has remained enigmatic. Based on the Drosophila Orai stru...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6102135/ https://ncbi.nlm.nih.gov/pubmed/29954946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003424 |
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