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Cross-linking of Orai1 channels by STIM proteins
The transmembrane docking of endoplasmic reticulum (ER) Ca(2+)-sensing STIM proteins with plasma membrane (PM) Orai Ca(2+) channels is a critical but poorly understood step in Ca(2+) signal generation. STIM1 protein dimers unfold to expose a discrete STIM–Orai activating region (SOAR1) that tethers...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
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| Päätekijät: | , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899466/ https://ncbi.nlm.nih.gov/pubmed/29581306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720810115 |
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