Molecular mechanisms of inhibition on STIM1-Orai1 mediated Ca(2+) entry induced by 2-aminoethoxydiphenyl borate

Store operated Ca(2+) entry (SOCE) mediated by STIM1 and Orai1 is crucial for Ca(2+) signaling and homeostasis in most cell types. 2-aminoethoxydiphenyl borate (2-APB) is a well described SOCE inhibitor but its action remains largely elusive. Here we show that 2-APB does not affect the dimeric state...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Pflugers Arch
Autori principali: Wei, Ming, Zhou, Yandong, Sun, Aomin, Ma, Guolin, He, Lian, Zhou, Lijuan, Zhang, Shuce, Liu, Jin, Zhang, Shenyuan L., Gill, Donald L., Wang, Youjun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393042/
https://ncbi.nlm.nih.gov/pubmed/27726010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1880-z
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi