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The Short N-terminal Domains of STIM1 and STIM2 Control the Activation Kinetics of Orai1 Channels
STIM1 and STIM2 are dynamic transmembrane endoplasmic reticulum Ca(2+) sensors, coupling directly to activate plasma membrane Orai Ca(2+) entry channels. Despite extensive sequence homology, the STIM proteins are functionally distinct. We reveal that the short variable N-terminal random coil sequenc...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740537/ https://ncbi.nlm.nih.gov/pubmed/19487696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.010900 |
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