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The Short N-terminal Domains of STIM1 and STIM2 Control the Activation Kinetics of Orai1 Channels

STIM1 and STIM2 are dynamic transmembrane endoplasmic reticulum Ca(2+) sensors, coupling directly to activate plasma membrane Orai Ca(2+) entry channels. Despite extensive sequence homology, the STIM proteins are functionally distinct. We reveal that the short variable N-terminal random coil sequenc...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhou, Yandong, Mancarella, Salvatore, Wang, Youjun, Yue, Chanyu, Ritchie, Michael, Gill, Donald L., Soboloff, Jonathan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740537/
https://ncbi.nlm.nih.gov/pubmed/19487696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C109.010900
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