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Orai Channel Pore Properties and Gating by STIM: Implications from the Orai Crystal Structure

The Orai channels are unusual, yet prominent, calcium (Ca(2+)) signal mediators in most cell types. Orai proteins are structurally unique, having little sequence homology with other ion channels. They are also functionally unique with exceedingly high selectivity for Ca(2+), mediating both short-ter...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Rothberg, Brad S., Wang, Youjun, Gill, Donald L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746713/
https://ncbi.nlm.nih.gov/pubmed/23512988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2003971
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