mTOR integrates diverse inputs to guide the outcome of antigen recognition in T cells

Por Waickman, Adam T, Powell, Jonathan D.
Publicado em 2012

mTOR, metabolism, and the regulation of T-cell differentiation and function

Por Waickman, Adam T, Powell, Jonathan D.
Publicado em 2012

A Modified Model of T-Cell Differentiation Based on mTOR Activity and Metabolism

Por Powell, Jonathan D., Heikamp, Emily B., Pollizzi, Kristen N., Waickman, Adam T.
Publicado em 2013

CD73 Is Critical for the Resolution of Murine Colonic Inflammation

Por Bynoe, Margaret S., Waickman, Adam T., Mahamed, Deeqa A., Mueller, Cynthia, Mills, Jeffrey H., Czopik, Agnieszka
Publicado em 2012

Enhancement of tumor immunotherapy by deletion of the A(2A) adenosine receptor

Por Waickman, Adam T., Alme, Angela, Senaldi, Liana, Zarek, Paul E., Horton, Maureen, Powell, Jonathan D.
Publicado em 2011

Cellular Size as a Means of Tracking mTOR Activity and Cell Fate of CD4+ T Cells upon Antigen Recognition

Por Pollizzi, Kristen N., Waickman, Adam T., Patel, Chirag H., Sun, Im Hong, Powell, Jonathan D.
Publicado no PLoS One (2015)

Regulation of CD4(+) and CD8(+) Effector Responses by Sprouty-1

Por Collins, Sam, Waickman, Adam, Basson, Albert, Kupfer, Abraham, Licht, Jonathan D., Horton, Maureen R., Powell, Jonathan D.
Publicado em 2012

CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis

Por Mills, Jeffrey H., Thompson, Linda F., Mueller, Cynthia, Waickman, Adam T., Jalkanen, Sirpa, Niemela, Jussi, Airas, Laura, Bynoe, Margaret S.
Publicado em 2008

CD4 effector T cell differentiation is controlled by IL-15 that is expressed and presented in trans

Por Waickman, Adam T., Ligons, Davinna L., Hwang, SuJin, Park, Joo-Young, Lazarevic, Vanja, Sato, Noriko, Hong, Changwan, Park, Jung-Hyun
Publicado no Cytokine (2017)

mTORC1 and mTORC2 selectively regulate CD8(+) T cell differentiation

Por Pollizzi, Kristen N., Patel, Chirag H., Sun, Im-Hong, Oh, Min-Hee, Waickman, Adam T., Wen, Jiayu, Delgoffe, Greg M., Powell, Jonathan D.
Publicado no J Clin Invest (2015)

The mammalian Target of Rapamycin (mTOR) regulates T helper cell differentiation through the selective activation of mTORC1 and mTORC2 signaling

Por Delgoffe, Greg M., Pollizzi, Kristen N., Waickman, Adam T., Heikamp, Emily, Meyers, David J., Horton, Maureen R., Xiao, Bo, Worley, Paul F., Powell, Jonathan D.
Publicado em 2011

Ischemia Induced Neuroinflammation is Associated with Disrupted Development of Oligodendrocyte Progenitors in a Model of Periventricular Leukomalacia

Por Falahati, Sina, Breu, Markus, Waickman, Adam T., Phillips, Andre W., Arauz, Edwin J., Snyder, Sophie, Porambo, Michael, Goeral, Katharina, Comi, Anne, Wilson, Mary Ann, Johnston, Michael V., Fatemi, Ali
Publicado em 2013

Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8 T cell differentiation

Por Pollizzi, Kristen N., Sun, Im-Hong, Patel, Chirag H., Lo, Ying-Chun, Oh, Min-Hee, Waickman, Adam T., Tam, Ada J., Blosser, Richard L., Wen, Jiayu, Delgoffe, Greg M., Powell, Jonathan D.
Publicado no Nat Immunol (2016)

Macrophage A2A Adenosinergic Receptor Modulates Oxygen-Induced Augmentation of Murine Lung Injury

Por Aggarwal, Neil R., D’Alessio, Franco R., Eto, Yoshiki, Chau, Eric, Avalos, Claudia, Waickman, Adam T., Garibaldi, Brian T., Mock, Jason R., Files, Daniel C., Sidhaye, Venkataramana, Polotsky, Vsevolod Y., Powell, Jonathan, Horton, Maureen, King, Landon S.
Publicado em 2013

Activated T cells secrete an alternatively spliced form of γc that inhibits cytokine signaling and exacerbates inflammatory autoimmune disease

Por Hong, Changwan, Luckey, Megan A., Ligons, Davinna L., Waickman, Adam T., Park, Joo-Young, Kim, Grace Y., Keller, Hilary R., Etzensperger, Ruth, Tai, Xuguang, Lazarevic, Vanja, Feigenbaum, Lionel, Catalfamo, Marta, Walsh, Scott T. R., Park, Jung-Hyun
Publicado em 2014

The AGC kinase serum- and glucocorticoid-regulated kinase 1 (SGK1) regulates T(H)1 and T(H)2 differentiation downstream of mTORC2

Por Heikamp, Emily B., Patel, Chirag H., Collins, Sam, Waickman, Adam, Oh, Min-Hee, Sun, Im-Hong, Illei, Peter, Sharma, Archna, Naray-Fejes-Toth, Aniko, Fejes-Toth, Geza, Sen, Jyoti, Horton, Maureen R., Powell, Jonathan D.
Publicado no Nat Immunol (2014)

Akt and mTOR pathways differentially regulate the development of natural and inducible T(H)17 cells

Por Kim, Jiyeon S., Sklarz, Tammarah, Banks, Lauren, Gohil, Mercy, Waickman, Adam T., Skuli, Nicolas, Krock, Bryan L., Luo, Chong T., Hu, Weihong, Pollizzi, Kristin N., Li, Ming O., Rathmell, Jeffrey C., Birnbaum, Morris J., Powell, Jonathan D., Jordan, Martha S., Koretzky, Gary A.
Publicado em 2013

Retraction: Natural and inducible T(H)17 cells are regulated differently by Akt and mTOR pathways

Por Kim, Jiyeon S, Sklarz, Tammarah, Banks, Lauren B, Gohil, Mercy, Waickman, Adam T, Skuli, Nicolas, Krock, Bryan L, Luo, Chong T, Hu, Weihong, Pollizzi, Kristin N, Li, Ming O, Rathmell, Jeffrey C, Birnbaum, Morris J, Powell, Jonathan D, Jordan, Martha S, Koretzky, Gary A
Publicado no Nat Immunol (2014)

Resolution of experimental lung injury by Monocyte-derived inducible nitric oxide synthase (iNOS)

Por D’Alessio, Franco R., Tsushima, Kenji, Aggarwal, Neil R., Mock, Jason R., Eto, Yoshiki, Garibaldi, Brian T., Files, Daniel C., Avalos, Claudia R., Rodriguez, Jackie V., Waickman, Adam T., Reddy, Sekhar P., Pearse, David B., Sidhaye, Venkataramana K., Hassoun, Paul M., Crow, Michael T., King, Landon S.
Publicado em 2012

An Fc Domain Protein–Small Molecule Conjugate as an Enhanced Immunomodulator

Por Chiang, Meng-Jung, Holbert, Marc A., Kalin, Jay H., Ahn, Young-Hoon, Giddens, John, Amin, Mohammed N., Taylor, Martin S., Collins, Samuel L., Chan-Li, Yee, Waickman, Adam, Hsiao, Po-Yuan, Bolduc, David, Leahy, Daniel J., Horton, Maureen R., Wang, Lai-Xi, Powell, Jonathan D., Cole, Philip A.
Publicado em 2014