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mTOR integrates diverse inputs to guide the outcome of antigen recognition in T cells

T cells must integrate a diverse array of intrinsic and extrinsic signals upon antigen recognition. While these signals have canonically been categorized into three distinct events - Signal 1 (TCR engagement), Signal 2 (co-stimulation or inhibition), and Signal 3 (cytokine exposure) - it is now appr...

詳細記述

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書誌詳細
主要な著者: Waickman, Adam T, Powell, Jonathan D.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3347776/
https://ncbi.nlm.nih.gov/pubmed/22556133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103143
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