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All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells

The mechanistic target of rapamycin (mTOR) is emerging as playing a central role in regulating T cell activation, differentiation, and function. mTOR integrates diverse signals from the immune microenvironment to shape the outcome of T cell receptor (TCR) antigen recognition. Phosphatidylinositol 3-...

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Bibliografiske detaljer
Main Authors: Gamper, Christopher J., Powell, Jonathan D.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3466461/
https://ncbi.nlm.nih.gov/pubmed/23087689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00312
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