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The PI 3-Kinase and mTOR Signaling Pathways Are Important Modulators of Epithelial Tubule Formation

Using MDCK cells as a model system, evidence is presented demonstrating that the signaling pathways mammalian target of rapamycin (mTOR) and phosphoinositide 3-kinase (PI 3-kinase) play important roles in the regulation of epithelial tubule formation. Incubation of cells with collagen gel overlays i...

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Bibliografiske detaljer
Udgivet i:J Cell Physiol
Main Authors: WALID, SHEREAF, EISEN, RANDI, RATCLIFFE, DON R., DAI, KEZHI, HUSSAIN, M. MAHMOOD, OJAKIAN, GEORGE K.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4371862/
https://ncbi.nlm.nih.gov/pubmed/18366086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21419
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