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Targeting the PI3-kinase/Akt/mTOR Signaling Pathway
This article presents an overview of the PI3K/Akt/mTOR signaling pathway. As a central regulator of cell growth, protein translation, survival, and metabolism, activation of this signaling pathway contributes to the pathogenesis of many tumor types. Biochemical and genetic aberrations of this pathwa...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3811932/ https://ncbi.nlm.nih.gov/pubmed/24012393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.soc.2013.06.008 |
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