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Comparison of Akt/mTOR Signaling in Primary Breast Tumors and Matched Distant Metastases
BACKGROUND: The Akt/mammalian target of the rapamycin (mTOR) signaling pathway represents a promising target for cancer therapy. The phosphorylation status of Akt and of mTOR's phosphorylation target eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) is often used to assess the activity...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819051/ https://ncbi.nlm.nih.gov/pubmed/18386830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.23456 |
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