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Targeting the mTOR Signaling Network for Cancer Therapy
The serine-threonine kinase mammalian target of rapamycin (mTOR) plays a major role in the regulation of protein translation, cell growth, and metabolism. Alterations of the mTOR signaling pathway are common in cancer, and thus mTOR is being actively pursued as a therapeutic target. Rapamycin and it...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Clinical Oncology
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738634/ https://ncbi.nlm.nih.gov/pubmed/19332717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.20.0766 |
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