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mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy

The mammalian or mechanistic target of rapamycin (mTOR) pathway plays a crucial role in regulation of cell survival, metabolism, growth and protein synthesis in response to upstream signals in both normal physiological and pathological conditions, especially in cancer. Aberrant mTOR signaling result...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Tian, Tian, Li, Xiaoyi, Zhang, Jinhua
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387042/
https://ncbi.nlm.nih.gov/pubmed/30754640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030755
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