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mTOR Signaling in Cancer and mTOR Inhibitors in Solid Tumor Targeting Therapy

The mammalian or mechanistic target of rapamycin (mTOR) pathway plays a crucial role in regulation of cell survival, metabolism, growth and protein synthesis in response to upstream signals in both normal physiological and pathological conditions, especially in cancer. Aberrant mTOR signaling result...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Tian, Tian, Li, Xiaoyi, Zhang, Jinhua
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6387042/
https://ncbi.nlm.nih.gov/pubmed/30754640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030755
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