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Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy

Small molecule inhibitors that selectively target cancer cells and not normal cells would be valuable anti-cancer therapeutics. The mammalian target of rapamycin complex 2 (mTORC2) is emerging as a promising candidate target for such an inhibitor. Recent studies in cancer biology indicate that mTORC...

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Autors principals: Sparks, CA, Guertin, DA
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3031870/
https://ncbi.nlm.nih.gov/pubmed/20418915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2010.139
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