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Targeting mTOR for cancer therapy
Mechanistic target of rapamycin (mTOR) is a protein kinase regulating cell growth, survival, metabolism, and immunity. mTOR is usually assembled into several complexes such as mTOR complex 1/2 (mTORC1/2). In cooperation with raptor, rictor, LST8, and mSin1, key components in mTORC1 or mTORC2, mTOR c...
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| Udgivet i: | J Hematol Oncol |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6612215/ https://ncbi.nlm.nih.gov/pubmed/31277692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0754-1 |
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