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Targeting mTOR network in colorectal cancer therapy
The mechanistic target of rapamycin (mTOR) integrates growth factor signals with cellular nutrient and energy levels and coordinates cell growth, proliferation and survival. A regulatory network with multiple feedback loops has evolved to ensure the exquisite regulation of cell growth and division....
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Baishideng Publishing Group Co., Limited
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989954/ https://ncbi.nlm.nih.gov/pubmed/24764656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v20.i15.4178 |
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