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mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges

Mammalian target of rapamycin (mTOR) regulates cell proliferation, autophagy, and apoptosis by participating in multiple signaling pathways in the body. Studies have shown that the mTOR signaling pathway is also associated with cancer, arthritis, insulin resistance, osteoporosis, and other diseases....

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Pubblicato in:Cell Biosci
Autori principali: Zou, Zhilin, Tao, Tao, Li, Hongmei, Zhu, Xiao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063815/
https://ncbi.nlm.nih.gov/pubmed/32175074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00396-1
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