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mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges

Mammalian target of rapamycin (mTOR) regulates cell proliferation, autophagy, and apoptosis by participating in multiple signaling pathways in the body. Studies have shown that the mTOR signaling pathway is also associated with cancer, arthritis, insulin resistance, osteoporosis, and other diseases....

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Biosci
Main Authors: Zou, Zhilin, Tao, Tao, Li, Hongmei, Zhu, Xiao
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063815/
https://ncbi.nlm.nih.gov/pubmed/32175074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00396-1
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