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mTOR signaling pathway and mTOR inhibitors in cancer: progress and challenges

Mammalian target of rapamycin (mTOR) regulates cell proliferation, autophagy, and apoptosis by participating in multiple signaling pathways in the body. Studies have shown that the mTOR signaling pathway is also associated with cancer, arthritis, insulin resistance, osteoporosis, and other diseases....

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Detalhes bibliográficos
Publicado no:Cell Biosci
Main Authors: Zou, Zhilin, Tao, Tao, Li, Hongmei, Zhu, Xiao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7063815/
https://ncbi.nlm.nih.gov/pubmed/32175074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-020-00396-1
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