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Targeting the PI3-kinase/Akt/mTOR Signaling Pathway
This article presents an overview of the PI3K/Akt/mTOR signaling pathway. As a central regulator of cell growth, protein translation, survival, and metabolism, activation of this signaling pathway contributes to the pathogenesis of many tumor types. Biochemical and genetic aberrations of this pathwa...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3811932/ https://ncbi.nlm.nih.gov/pubmed/24012393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.soc.2013.06.008 |
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