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mTOR-Dependent and Independent Survival Signaling by PI3K in B Lymphocytes
Peripheral B lymphocyte survival requires the B cell receptor (BCR) and B cell activating factor (BAFF) binding to its receptor (BAFF-R). Deletion of the BCR, or its signal transducing chaperone Igβ, leads to rapid loss of mature B cells, indicating that signals initiated at the BCR are crucial for...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4718598/ https://ncbi.nlm.nih.gov/pubmed/26785352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146955 |
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