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mTOR integrates diverse inputs to guide the outcome of antigen recognition in T cells
T cells must integrate a diverse array of intrinsic and extrinsic signals upon antigen recognition. While these signals have canonically been categorized into three distinct events - Signal 1 (TCR engagement), Signal 2 (co-stimulation or inhibition), and Signal 3 (cytokine exposure) - it is now appr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3347776/ https://ncbi.nlm.nih.gov/pubmed/22556133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103143 |
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