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mTOR, metabolism, and the regulation of T-cell differentiation and function
Upon antigen recognition, naive T cells undergo rapid expansion and activation. The energy requirements for this expansion are formidable, and T-cell activation is accompanied by dramatic changes in cellular metabolism. Furthermore, the outcome of antigen engagement is guided by multiple cues derive...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419491/ https://ncbi.nlm.nih.gov/pubmed/22889214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2012.01152.x |
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