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The mammalian Target of Rapamycin (mTOR) provides a critical link between T cell differentiation, function and metabolism
In the two signal model of T cell activation, the outcome of antigen recognition is determined by the integration of multiple cues in the immune microenvironment. mTOR is an evolutionarily conserved PI3-kinase family member that plays a central role in integrating environmental cues in the form of a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2962404/ https://ncbi.nlm.nih.gov/pubmed/20870173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.09.002 |
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