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The mammalian Target of Rapamycin (mTOR) provides a critical link between T cell differentiation, function and metabolism

In the two signal model of T cell activation, the outcome of antigen recognition is determined by the integration of multiple cues in the immune microenvironment. mTOR is an evolutionarily conserved PI3-kinase family member that plays a central role in integrating environmental cues in the form of a...

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Sonraí Bibleagrafaíochta
Main Authors: Powell, Jonathan D., Delgoffe, Greg M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2962404/
https://ncbi.nlm.nih.gov/pubmed/20870173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.09.002
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